Logo of Phnom Penh Post newspaper Phnom Penh Post - Vietnamese scientists have made potential cancer breakthrough

Vietnamese scientists have made potential cancer breakthrough

Content image - Phnom Penh Post
Scientists of the Vietnam Academy of Science and Technology (Vast). VIET NAM NEWS

Vietnamese scientists have made potential cancer breakthrough

Scientists of the Vietnam Academy of Science and Technology (Vast) have succeeded in synthesising platinum complexes which have cytotoxicity on cancer cells and have the potential for treating cancer.

The research was recognised as outstanding and accepted by Vast’s Appraisal Council on June 18.

“Cancer is on the rise in Vietnam and around the world. Although scientists have made great efforts in producing anti-cancer drugs, they have not met demand and the mortality rate among cancer patients is still high,” said Nguyen Quang Trung, from the Institute of Chemistry of Vast, the leading author of the research.

A research paper entitled “Synthesis, characterization and In Vitro Cytotoxicity of Palatinum (II) complexes with Some Tetradentate Salen Ligands” was published in Science Journal of Chemistry on July 1 last year.

Cisplatin is a widely used drug across the world for the treatment of various cancers including ovarian and testicular cancer. However, it has severe side effects and drug resistance.

Medical chemists are exploring to overcome these obstacles by developing new platinum complexes which have different structural features and reactivities.

Trung and his colleagues have tried to create the platinum complexes that are effective in cancer treatment but minimise the side effects on patients.

In the research, they evaluated the in-vitro cytotoxicity of platinum complexes on human epidermoid carcinoma cells and breast cancer cells. The results showed the complexes have a positive effect on cancer cells.

Trung said: “These research results have strengthened and developed the direction of inorganic biochemical research in Vietnam, contributing to improving the skills of synthesising ligands and complexes for researchers.”

He also said it would help enhance capacity for studying the characterisation of platinum complex, especially cytotoxicity to cancer cells.



  • Without shoes or a helmet, a young cyclist steals the show

    Pech Theara gripped the curved handlebars of his rusty old bike, planted his bare feet on its pedals and stormed as fast as he could towards the finish line. The odds were against him as the 13-year-old faced off against kids with nicer bikes at

  • Phnom Penh-Sihanoukville expressway on schedule

    The construction of the more than $1.9 billion Phnom Penh-Sihanoukville Expressway has not been delayed despite the Covid-19 pandemic, with more than 26 per cent of the project completed and expected to finish in about two years, according to Ministry of Public Works and Transport secretary of

  • Singapore group seeks $14M in damages from PPSP over ‘breach of contract’

    Singapore-based Asiatic Group (Holdings) Ltd is seeking a minimum of $14.4 million relief from Cambodia Securities Exchange (CSX)-listed Phnom Penh Special Economic Zone Plc (PPSP) for allegedly breaching a power plant joint venture (JV) agreement. Asiatic Group’s wholly-owned Colben System Pte Ltd and 95 per

  • Over 110 garment factories close

    A government official said on November 22 that at least 110 garment factories had closed in the first nine months of the year and left more than 55,000 workers without jobs – but union leaders worry those numbers could be much higher. Ministry of Labour and Vocational Training undersecretary

  • PM dispels lockdown rumours, gifts masks

    Prime Minister Hun Sen on November 12 denied rumours that he will lock down the country in response to increased Covid-19 fears, referring to them as propaganda aimed at destabilising the country. In a Facebook post, he said some people had spread rumours that the government

  • SilkAir adds flight to Phnom Penh schedule

    Silkair (Singapore) Pte Ltd is increasing its flight frequency between Phnom Penh and Singapore with a third weekly flight on Saturdays, according to Cambodia Airports’ Facebook page. The other flights offered are on Tuesdays and Sundays, with an estimated Phnom Penh arrival time at 5:35pm